The embodiment of the invention discloses a music score page turning processing method and device. The method comprises the following steps of performing filtering processing on a preset audio to obtain a page turning note of a target musical instrument; obtaining the target audio in the music score playing process in real time; analyzing the target audio to obtain a target playing note; if the judging result shows that the target playing node is matched with the target page turning note, controlling the music score to execute the page turning operation. The device comprises an audio filteringmodule, an audio analysis module and a page turning control module. According to the embodiment of the invention, the playing note in the playing process is matched with the page turning audio so asto control the page turning of the music score, so that a player automatically completes the page turning of the music score in the playing process without the help by others; the method and the device are applicable to various music scores and musical instruments; the page turning is accurate; the cost is low.