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发明公开
CN109908145A 防己诺林-7-丙酸酯与酪氨酸激酶抑制剂的药物组合物 有权

防己诺林-7-丙酸酯与酪氨酸激酶抑制剂的药物组合物
摘要：
本发明涉及医药技术领域，具体的说，本发明公开一种防己诺林-7-丙酸酯(W6)与酪氨酸激酶抑制剂的药物组合物及其治疗耐药肝癌的用途，特别是防己诺林-7-丙酸酯与索拉非尼或瑞戈非尼的组合物在治疗耐药性肝癌方面，具有协同增敏和耐药逆转作用，可显著提高治疗耐药性肝癌的疗效。
摘要（英）：

The invention relates to the field of medical technology and particularly discloses a drug combination of fangchinoline-7-propionate (W6) and tyrosine kinase inhibitor and application thereof to treating drug-resistant liver cancer. Specifically, when applied to treating the drug-resistance liver cancer, the combination of the fangchinoline-7-propionate and sorafenib or regorafenib can achieve synergic sensibilization and drug resistance reversion and significantly improve the therapeutic effects on the drug-resistant liver cancer.

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