The invention relates to a sample clamping device for a high-temperature high-frequency complicated load loading test, and belongs to the technical field of material testing. The sample clamping device is composed of a left clamp and a right clamp which are same in structure; in the left clamp or the right clamp, an outer ring of a sleeve is matched with an inner ring of a knuckle bearing or a clamping part of a standard plate-shaped sample, is fixed through a quick-change baffle ring and is mounted on a supporting seat; an inner ring of the sleeve is provided with a thread, and is screwed with an outer thread section of a high-temperature high-frequency complicated load sample to realize the fixation of the high-temperature high-frequency complicated load sample; the bottom of the supporting seat is provided with four through holes, and is mounted on a tensile bending composite fatigue testing machine through bolts; and a tensile loading device on the testing machine is connected withthe supporting seat through bolts to realize the static tensile loading of the high-temperature high-frequency complicated load sample. The sample clamping device has the advantages as follows: the sample clamping device can be applicable to a material testing machine with loading functions of high temperature, tension, bending, ultrasonic vibration and the like; the sample clamping device is simple in structure and convenient in operation; and a powerful guarantee is provided for testing the mechanical properties of key structure materials in the fields of aviation, spaceflight and the like.