The invention relates to a quick and accurate hole making mechanism of a handle nut. The quick and accurate hole making mechanism of the handle nut is characterized by comprising an appearance positioning mechanism (1), a drilling mechanism (2) and positioning pins (3); the handle nut is mounted and positioned through a positioning groove in the appearance positioning mechanism (1); and the drilling mechanism (2) is installed and positioned through the positioning pins (3) and the appearance positioning mechanism (1). According to the quick and accurate hole making mechanism, the problems of low efficiency, poor precision and low interchangeability in the handle nut connecting hole drilling process are effectively solved, the structure is simple, the use is convenient, the application range is wide, and good quality benefits and economic benefits are obtained.