The embodiment of the invention relates to a method and device for unlicensed band communication and a computer readable storage medium. According to embodiments herein, a terminal device determines amodulation coding configuration for a plurality of uplink subframes, the modulation coding configuration indicating at least two modulation coding schemes in the plurality of uplink subframes. The terminal device determines an initial location in a plurality of uplink subframes, and performs the uplink transmission based on the initial location and the determined modulation coding configuration.According to embodiments herein, the terminal device employs at least two modulation encoding schemes to perform uplink transmission in an initial subframe and a subsequent subframe without having toprepare multiple versions of uplink transmission blocks for multiple possible initial positions, thereby reducing the implementation complexity of the terminal device. In particular, an uplink reception success rate at a network device will be improved in the case where a modulation coding scheme for an initial subframe is a predetermined low-order modulation coding scheme.