The invention relates to a post-partum depression alleviation and cognitive behavior training system based on a WeChat platform, belonging to the technical field of medical systems. The post-partum depression alleviation and cognitive behavior training system is communicated with maternity and child care institutions and medical institutions. The post-partum depression alleviation and cognitive behavior training system includes a system promotion unit, a pregnancy file establishment unit, an in-pregnancy detection unit, a prenatal evaluation unit, a postpartum cognitive behavior training unit,wherein the system promotion unit is provided with an online video explanation module and an offline scene solution module; the online video explanation module adopts a mode of 3D animation demonstration, and the offline scene solution module is provided with an online reservation module; and the reservation module is provided with a brief condition presentation module. The post-partum depressionalleviation and cognitive behavior training system evaluates the self situation and living environment of a pregnant woman from the early stage to assess, and controls the factors affecting the moodof the pregnant woman. The post-partum depression alleviation and cognitive behavior training system carries out interference on the conditions of a parturient postpartum by dividing the postpartum period into three stages, and adjusts the postnatal cognitive behavior.