The invention discloses a medical anti-pollution drying and unfreezing device. The medical anti-pollution drying and unfreezing device comprises a water tank, an article containing box and execution parts, wherein an unfreezing medium and a heating device for heating the unfreezing medium are arranged in the water tank, a guide rail is further arranged in the water tank, the article containing boxis connected to the guide rail through rolling wheels, and the execution part is connected with the article containing box; the execution parts comprise a motor, an eccentric wheel, a universal jointconnecting rod and a sliding shaft, wherein the sliding shaft is provided with two sliding bearings in a sleeved mode, a plurality of latex bags for containing substances to be unfrozen are arrangedin the article containing box, and the plurality of latex bags are connected with the article containing box through latex bag hanging plate assemblies. According to the device, the latex bag hangingplate assemblies are adopted to be installed on the article containing box, so that the substances to be unfrozen are not in direct contact with one another, meanwhile, the substances to be unfrozen are not in direct contact with the unfreezing medium, so that pollution among the substances to be unfrozen is avoided, cross contamination among the substances to be unfrozen and the unfreezing mediumis eliminated at the same time, and quick unfreezing can be carried out in a dry and independent environment.