The invention discloses an anti-corrosion antibacterial PE water supply pipe and a preparation method thereof and belongs to the technical field of water supply pipes. The anti-corrosion antibacterialPE water supply pipe is prepared from, by weight, 20-40 parts of polyethylene raw material, 5-15 parts of glycerol triacetate, 2-4 parts of 2-mercaptobenzimidazole, 1-3 parts of sodium polyacrylate,4-10 parts of N,N-di(2-ethylhexyl)-2-benzothiazole-sulphenamide, 5-9 parts of tris(nonylphenyl) phosphite, 4-10 parts of aminopropyltriethoxysilane, 3-9 parts of ferrous sulfate, 2-4 parts of ultra-fine fully-vulcanized powder rubber, and 2-4 parts of stabilizers. The invention further provides the preparation method of the anti-corrosion antibacterial PE water supply pipe. The anti-corrosion antibacterial PE water supply pipe has good corrosion resistance performance and good antibacterial property.