The invention discloses a fertilization method for reducing content of chlorine in flue-cured tobacco. The fertilization method comprises the following steps: 1) 30-40 days before the transplanting oftobacco plants, turning over and pressing with rice straws, wherein the turnover amount is 350-450kg/667m<2>; 2) 0-3 days before transplanting, and before the ridging of a tobacco field, mixing 20-30kg/667m<2> of a cake fertilizer with 20-30kg/667m<2> of a special tobacco composite fertilizer, and fertilizing in a strip manner; 3) 30 days after the tobacco transplanting, applying 20-30kg/667m<2>of potassium nitrate in a drip fertigation mode; 4) applying the potassium nitrate within 30-37 days, 37-44 days and 44-51 days after transplanting, and controlling a fertilizer concentration within 0.3-0.5% each time; 5) controlling the nitrogen, phosphorus and potassium ratio of all chemical fertilizers within 1-2.5 to 1-3.5. By adopting the fertilization method, the content of chlorine in the flue-cured tobacco can be effectively reduced, the quality and the industrial usability of the tobacco can be improved, the yield and the production value of the tobacco can be increased, the economical benefit of the tobacco can be increased, physical and chemical properties of tobacco planting soil can be improved, and the quality of the tobacco planting soil can be improved.