The invention discloses a manufacturing method of a centrifugal pump induction wheel. The manufacturing method comprises the following steps that (a) a shell is manufactured; (b) a liquid is injected;(c) vibration is carried out; (d) adjustment is carried out; and (e) post-processing is carried out. The manufacturing method is high in feasibility and easy to control, the induction wheel without parting surfaces can be cast, the forming quality is good, and the problems that the casting precision is poor, the surface defects are large and the quality of a finished product is low in a traditional manufacturing method are solved.