The invention provides a flexible display panel and a method of manufacturing the same. The flexible display panel has a bending zone, a first zone and a second zone, wherein the bending zone is located between the first zone and the second zone, and the flexible display panel comprises a buffer layer and a pixel unit. The buffer layer is disposed on the flexible substrate. The pixel unit is disposed on the buffer layer of the first zone. The buffer layer has impurities, wherein the concentration of the impurities in the bending zone is [M]; the concentration of the impurity in the first zoneis [M]1, and [M]1/[M]>1, or [M]1/[M]<0.1.