The invention relates to the technical field of module processing auxiliary devices, and especially relates to a liquid crystal module plastic frame paint spraying device, which can fix different sizes of plastic frames to reduce the use limitations; besides, a plastic frame can be turned over conveniently after painting one side of the plastic frame, thus the working efficiency is improved and the use reliability is improved; and meanwhile, paints can be prevented from polluting the working environment, the health of workers is protected, and the practicability is improved. The liquid crystalmodule plastic frame paint spraying device comprises a workbench, a spray gun, a box body, four groups of supporting columns, a top plate, a bottom plate, a rotating shaft, a limiting rod, a left threaded pipe, a first left threaded rod, a second left threaded rod, a right threaded pipe, a first right threaded rod, a second right threaded rod, a door plate, a first ball bearing, a tension springand a hook; the liquid crystal module plastic frame paint spraying device further comprises a rotating rod, a supporting plate, a second ball bearing, a first umbrella-shaped wheel, a second umbrella-shaped wheel, a handle, an exhaust fan, a processing box, a zeolite adsorption device, an exhaust pipe and a dust hood.