The invention provides a portable multi-function pen holder. The portable multi-function pen holder comprises an upper layer small stationery storage layer, a lower layer pen holder layer and a pen holder cover, wherein the pen holder layer and the storage layer can relatively rotate, and the pen holder cover is disposed at the top of the upper layer storage layer. The pen holder layer is in a cylinder shape with a closed lower end, and a vertical rotating pen holder shaft is fixedly disposed on the cylinder-shaped side wall. The storage layer is in a cylinder shape with an outer diameter equal to the outer diameter of the pen holder layer, and is rotatably fixed to the pen holder shaft around the pen holder shaft. The pen holder can simultaneously satisfy two single-sided requirements that students conveniently carry stationeries to a classroom and the use of the stationeries at home is convenient.