The invention discloses a PET (polyethylene terephthalate) precision infusion filtering nuclear pore membrane hydrophilization treatment process. The process is characterized by including steps of aninitiator bath preparation, initiating treatment, grafting bath preparation, grafting treatment and the like. The process is simple, safe and low in equipment requirement, membrane intrinsic mechanical performances and nuclear pore membrane structures are unchanged after treatment, membrane surface hydrophilicity can be remarkably enhanced, and accordingly air interception capacity, liquid retaining height, liquid flux of membranes can be increased, and low toxicity and high durability are realized. By adoption of the process, infusion functions of PET precision infusion filtering nuclear poremembranes can be improved, and infusion safety is improved.