The invention relates to a vertical rescue and drainage centrifugal pump. Structural innovation is conducted on the basis of a traditional vertical rescue and drainage centrifugal pump. A pressure relief chamber composed of a water throwing ring, a water outlet volute, a centrifugal impeller, an oil chamber lower cover and an oil chamber is designed in the upper portion of the centrifugal impeller, and the position of a pressure relief water hole is lower than that of the water throwing ring, so that the good operation environment of a double-end-face mechanical seal is ensured; and a plurality of flushing holes are designed in a water inlet front cover, and siltation of silt at an inlet of the centrifugal impeller is avoided.