The invention provides a preparation process of a degreasing green cleaning agent and relates to the technical field of cleaning agents. The preparation process comprises the following steps: S1, calcining bentonite, titanium dioxide, calcined kaolin, zirconium oxide, calcium carbonate and magnesium silicate at a high temperature and at a high pressure to prepare a nano abrasive material; and S2,uniformly mixing the nano abrasive material, 13-23 parts of hydroxy carboxylic acid, 17-25 parts of sodium dodecyl benzene sulfonate, 8-15 parts of xylene, 9-21 parts of a moutan bark extract, 11-21 parts of diethylenetriamine, 15-25 parts of heptane, 4-12 parts of emulsified oil, 2-5 parts of a foaming agent and 70-120 parts of deionized water, and leaving the mixture to stand to prepare the degreasing green cleaning agent. According to the preparation process of the degreasing green cleaning agent, provided by the invention, on the basis of a water-based cleaning agent, a formula of the water-based cleaning agent is adjusted, and the nano abrasive material is added. Oil stains are removed quickly and effectively by means of friction and action of air bubbles, so that a very ideal degreasing cleaning effect is achieved.