The invention belongs to the technical field of coal mine gas treatment, and relates to an oxidation device containing a combined porous medium charge and a loading method thereof. The oxidation device includes a regenerative incinerator, a fan and a chimney. Air inlet chambers under a first heat storage body and a second heat storage body are correspondingly communicated with the fan through airinlet pipes with air inlet valves, the first heat storage body and the second heat storage body are provided with , in order from bottom to top, a water absorbing layer filled with a water absorbing material, a heat storage layer filled with an inert heat storage filler, and a catalytic coating for uniformly dispersing the catalyst in the heat storage filler. The upper part of a regenerative incinerator is provided with a combustion chamber which is provided with a burner, and a flue gas passage is arranged above the combustion chamber. The oxidation device containing the combined porous medium charge and the loading method thereof solve the problem that all the inertia fillers in the heat storage body are filled in the prior art, and the water vapor in the coal mine gas is easily enteredinto the heat storage body, the catalytic efficiency of the catalyst in the heat storage body is reduced, and the effect of purifying the coal mine gas and the heat energy recovery effect are reduced.