The invention discloses a non-slip brick. The non-slip brick comprises a green body, a ground coat enamel layer, a cover coat enamel layer and a non-slip enamel layer, wherein the ground coat enamel layer is disposed between the green body and the cover coat enamel layer; the cover coat enamel layer is disposed between the ground coat enamel layer and the non-slip enamel layer; a ground coat enamel used by the ground coat enamel layer includes a ground coat enamel additive; the ground coat enamel additive is a C5 resin solution; the C5 resin solution is a solution with C5 resin as a solute, cyclohexane as a solvent and a mass concentration of 5-8%; a cover coat enamel used by the cover coat enamel layer includes a cover coat enamel additive; the cover coat enamel additive is yttrium oxide;a non-slip enamel used by the non-slip enamel layer includes a non-slip enamel additive; the non-slip enamel additive is sodium chloride; the thickness of the non-slip enamel layer is 0.5-2 mm. A preparation method of the non-slip brick comprises the following steps of molding the green body, spraying the ground coat enamel, spraying the cover coat enamel, performing inkjet-printing, spraying thenon-slip enamel, firing and performing after-treatment to obtain a finished product. According to the non-slip brick and the preparation method thereof disclosed by the invention, the obtained non-slip brick has good non-slip performance, high bending strength and good thermal shock resistance.