The invention relates to the technical field of pipeline processing, in particular to a device capable of uniform rust removal and paint spraying for a pipeline. The device comprises a shell, a secondthreaded rod is horizontally installed on the upper portion of the inner side of the shell, one end of the second threaded rod is rotationally connected with the inner wall of the shell, the lower surface of a first threaded sliding block is provided with a derusting device, a telescopic device is hinged to the upper surface of each second supporting plate through a hinge shaft, one end of each telescopic device penetrates through the shell and is fixedly connected with a clamping device, first electric telescopic rods are symmetrically arranged on one side of the inner upper surface of the shell, a square groove is formed in the upper surface of a movable frame, the two sides of the upper surface of the movable frame are correspondingly provided with second mounting blocks, and a fourththreaded rod is connected between the two second mounting blocks. According to the device, the labor force can be reduced, the structure is simple, rapid rust removal and paint spraying of the pipeline can be realized, so that the production efficiency of the pipeline is improved; and meanwhile, the rust removal and paint spraying effects are good, and the device is worthy of being widely popularized and used.