The invention relates to a guide rail device for lifting. The guide rail device comprises a rail mechanism, a supporting mechanism, a sliding mechanism and a connecting mechanism; the rail mechanism comprises a rail which is horizontally arranged and a sliding way which is arranged under the rail and is parallel to the rail, and the upper end face and the lower end face of the rail are provided with multiple grooves of which the extending directions are consistent with that of the rail; the supporting mechanism comprises supporting fixing parts arranged at the two ends of the rail and the sliding way; the sliding mechanism comprises a sliding part arranged outside the rail in a sleeving mode, a sleeve part which is of a U-shaped structure is installed outside the sliding part in a sleevingmode, the upper end face and the lower end face, making contact with the rail, of the sliding part are provided with convex strips corresponding to the grooves, a baffle rod which is transversely arranged is arranged on the portion, located under the sliding part, of the interior of the sleeve part, and a rolling wheel is arranged under the sliding part and slidably arranged on the sliding way; and the connecting mechanism comprises a connecting part which is of an H-shaped structure and movably connected with the sleeve part. The guide rail device for lifting has the advantages that the structure is simple, noise is low, and the lifting flexibility and stability are improved.