The invention provides a routing table information configuration system and method and relates to the technical field of information configuration. The system comprises a common information configuration module, a broadcast configuration module and a per-port configuration module. The common information configuration module is used for configuring a common routing table. The common routing table comprises the following information: selection information of a target default port, RapidIO domain information and multicast mask information. The broadcast configuration module is used for configuring a broadcast routing table. The per-port configuration module is used for configuring a per-port routing table. The per-port routing table comprises the following information: per-port device table information and per-port domain table information. According to the system and the method, the technical problem that in the prior art, the register routing table information configuration efficiency is low due to the fact that routing table information of only one register is configured and managed at one time is solved. According to the system and the method, the technical effect of configuring and managing a plurality of registers at one time and improving the register information configuration efficiency is achieved.