The invention provides a digestive tract foreign body removal device applicable to different sizes and different materials. Arc-shaped pushing and pressing pieces are symmetrically arranged at both sides of a bag body, wherein the back ends of the arc-shaped pushing and pressing pieces are movably hinged with the end portion of the front end of an arc-shaped connecting piece, a drawing piece is arranged at the back end of the connecting piece, the end portions of the front ends of the arc-shaped pushing and pressing pieces are provided with pushing and pressing pieces, a vacuum negative pressure principle is adopted, the pushing and pressing pieces preclude air in the bag body, when an opening presses or contacts foreign bodies, pressure of the bag body is released, so that the foreign bodies are absorbed in the opening or inhaled into the bag body, the digestive tract foreign body removal device is applicable to different sizes of foreign bodies, and multiple bag bodies with differentsizes do not need to be prefabricated, thereby reducing the production and use cost; an opening baffle assembly outside the bag body enables a shielding part and a limiting part to be pressed on thebag body through an opening baffle, a baffle sliding groove and a baffle push-pull rod and a torsional spring arranged on the shielding part and limiting part of the opening baffle, and the shieldingpart is shielded under the acting force of the torsional spring in an opening when moving to the opening, thereby improving the stability of diagnosis and treatment.