The invention discloses application of betulinic acid and derivatives thereof in control of rice planthoppers and provides novel application of betulinic acid and derivatives thereof for agriculturalproduction, namely application of betulinic acid and derivatives thereof serving as pesticides in control of rice planthoppers. The pesticide preparations prepared from the betulinic acid and derivatives thereof are high in activity and low in toxicity, have excellent control effects on the rice planthoppers, and are ideal pesticides for controlling the rice planthoppers.