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CN108700594A 多囊性肾病的生物标志物及其用途 有权

  • Patent Title: 多囊性肾病的生物标志物及其用途
  • Patent Title (English): Biomarker of polycystic kidney disease and uses thereof
  • Application No.: CN201680079045.X
    Application Date: 2016-11-15
  • Publication No.: CN108700594A
    Publication Date: 2018-10-23
  • Inventor: N·布卡诺夫 , S·莫雷诺 , T·E·威登
  • Applicant: 建新公司
  • Applicant Address: 美国马萨诸塞州
  • Assignee: 建新公司
  • Current Assignee: 建新公司
  • Current Assignee Address: 美国马萨诸塞州
  • Agency: 北京坤瑞律师事务所
  • Agent 谢梦欣
  • Priority: 62/257,089 20151118 US
  • International Application: PCT/US2016/062075 2016.11.15
  • International Announcement: WO2017/087409 EN 2017.05.26
  • Date entered country: 2018-07-16
  • Main IPC: G01N33/68
  • IPC: G01N33/68
多囊性肾病的生物标志物及其用途
Abstract:
本文提供了用于确定患者中的多囊性肾病(PKD)的治疗功效、诊断患者中的PKD、对患者中的PKD进行分期、以及监测患者中的PKD的方法。这些方法包括确定AMBP的单个或多个水平。还提供了包含特异性结合至AMBP蛋白的抗体和特异性结合至PKD另外的标志物的至少一种抗体的试剂盒。
Abstract(English):

Provided herein are methods for determining the efficacy of treatment for polycystic kidney disease (PKD) in a patient, diagnosing PKD in a patient, staging PKD in a patient, and monitoring PKD in a patient. These methods include determining a single or multiple levels of AMBP. Also provided are kits that include an antibody specifically binds to AMBP protein and at least one antibody that specifically binds to an additional marker of PKD.

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