The invention provides a method for assessing the vulnerability of a regional distribution network and relates to the technical field of power supply. The method is used for solving a problem that a vulnerability assessment method in the prior art is difficult to apply to a regional power grid. The method comprises the steps of (1) delineating the regional power grid, (2) determining various indicators in the regional power grid described in step (1) and setting a weight for each indicator separately, (3) scoring each indicator described in step (2), (4) obtaining a total score of the regionalpower grid by using a weighting method, and (5) judging the vulnerability of the regional power grid based on the total score of the regional power grid, wherein the lower the total score is, the more vulnerable the power grid is. The method has the advantages that the method is applied to the vulnerability assessment of the regional power grid under a high-permeability distributed power access condition, and the method has accurate and practical evaluation.