The invention provides a method for automatically generating a substation operation order. The method comprises simulating a typical interval of a substation, generating an operation rule of each device according to a five-prevention logic, generating a primary connection diagram according to an actual situation in the substation and in combination with the typical interval, extracting the currentstate and the target state of the corresponding interval device by analyzing an operation input instruction, transferring the current state to the target state by a solving algorithm, continuouslydetermining whether a device state is the target state, and adding operable devices to an operation sequence to automatically generate the operation order. The method can solve the low efficiency of generating the operation order in the substation and the poor universality of an operation order system.