The invention discloses a cleaning device for medical instruments. The cleaning device comprises a device body; a base is arranged at the lower end of the device body; a motor is mounted inside the base; a rotating rod is mounted at the output end of the motor; stirring blades are arranged on the outer side of the rotating rod; bearing plates are arranged on the inner wall of the device body; first fixing blocks and second fixing blocks are arranged at the upper ends of the bearing plates respectively; the inner sides of the second fixing blocks are connected with extruding plates through springs; sliding grooves are formed inside the bearing plates; sliding blocks matched with the sliding grooves are arranged at the lower ends of the extruding plates; a first nozzle and a second nozzle are arranged at the upper part of the device body respectively and are connected with water inlet pipes; and electric heaters are arranged at the bottom end of the device body. The cleaning device adopts the simple structure, is quick and convenient in cleaning, can save time and physical strength, has the better cleaning effect, can avoid falling damage to the instruments, and is safe and convenient to use.