The invention discloses a paper pressing device with a prelimiting device for a printing machine. The paper pressing device comprises a machine frame, a paper placing workbench, a paper pile, a paperpressing device body and the prelimiting device. The machine frame comprises a pair of front and rear supports which are arranged in a front-rear symmetrical mode, and the paper pressing device body comprises a pair of paper pressing supporting plates arranged in a lifting mode and a pair of pressing rollers arranged in a left-right symmetrical mode. A pair of rectangular limiting driving groovesarranged in a left-right symmetrical mode are formed inside the paper pressing supporting plates, rectangular sliding wire grooves are formed in the lower ends of the front side wall and the rear sidewall of the limiting driving grooves, and front-rear-through rectangular avoiding grooves matched with the sliding wire grooves are formed in the lower ends of the oppositely-close side walls of thepair of limiting driving grooves, rectangular limiting plates are arranged in the limiting driving grooves in a lifting mode, a pair of left-right symmetrical prelimiting columns are formed on the upper end face of a lifting bottom plate, and rectangular top plates are formed in the middles of the prelimiting columns. By means of the paper pressing device, the paper pressing efficiency can be improved, and paper flatness is ensured.