The invention provides a data desensitization method and device. The method comprises the following steps of: receiving to-be-desensitized original data in real time; respectively desensitizing the original data by adoption of a first desensitization algorithm and a second desensitization algorithm so as to obtain first desensitized data and second desensitized data, and obtaining the first desensitized data and the second desensitized data in to-be-analyzed data; and if second encrypted data of the second desensitized data is same as preset second encrypted data, analyzing the second desensitized data and returning an analysis result, wherein the analysis result is the original data.