The invention discloses a thin film intaglio printing spot-color matching method. The thin film intaglio printing spot-color matching method specifically comprises the steps that by collecting the spectral reflectivities of primary color printing ink and target color printing ink on a transparent thin film and a substrate, the spectral reflectivities and transmissivities of the primary color printing ink and the target color printing ink are worked out; then the spectral transmission densities of the primary color printing ink and the target color printing ink are worked out by means of the obtained spectral transmissivities; and finally, a spectral transmission density curve is drawn by means of the obtained spectral transmission densities, a printing ink formula prediction model is builtby means of the spectral transmission density curve and subjected to programming solving, and thus the primary color printing ink proportion of the target color printing ink is obtained. From the spectral reflectance and transmission characteristics of the printing ink, the effects and functions of the substrate on light absorbing are excluded, and the formula prediction model is built by means of the spectral transmission densities of the printing ink. According to the method, the disturbance of environments and human factors on printing ink color matching can be reduced, color matching precision can be effectively improved, and a theoretical basis and the experimental method are provided for thin film intaglio printing spot-color matching.