The invention discloses a simulation system and a simulation method for power equipment in a communication base station machine room based on a serial port. A simulator is used for simulating variouskinds of power equipment, and the simulation system is connected with monitoring unit to be monitored via the serial port, so that various kinds of equipment adaptation detection can be performed on the monitoring unit, the various kinds of power equipment can be simulated according to the serial port parameter and communication protocol of various kinds of power equipment, the various kinds of power equipment can be simulated, and thus the adaptation of the monitoring unit can be quickly and efficiently detected, the detection cost can be reduced, and the detection time can be saved.