A method and system to control a refrigeration unit (104) in response to a cargo load (108) in a refrigerated container includes providing a plurality of sensors disposed within the refrigerated container, providing a cargo load temperature range and a cargo load excursion time limit corresponding to the cargo load, receiving a plurality of temperature readings corresponding to the cargo load viathe plurality of sensors, operating the refrigeration unit in a power saving mode in response to the plurality of temperature readings within the cargo load temperature range, and operating the refrigeration unit in a standard mode in response to the plurality of temperature readings outside the cargo load temperature range for longer than the cargo load excursion time limit.