The invention belong to the field of sulphuric acid production equipment, and particularly relates to an industrial sulphuric acid solid-liquid separation system, comprising a reaction tank, a filtering module and an extrusion module; the top end of the filtering module is fixedly connected with a rotary shaft of a motor by a No. 1 rotating rod, and the lower end of the filtering module is rotationally mounted on the inner surface of a lower bottom plate of the reaction tank; the extrusion module extrudes the surface of the filtering module to discharge liquid in the filtering module; the bottom of a side surface of the reaction tank is provided with a No. 1 liquid outlet, the center of the lower bottom plate of the reaction tank is provided with a No. 1 liquid inlet, and the lower bottomplate of the reaction tank is provided with a No. 1 material outlet. The industrial sulphuric acid solid-liquid separation system is mainly used for performing desulfuration treatment on a solution ofiron pyrite roasting flue gas, extrusion type filtering can be performed on sulphuric acid waste, and the desulfuration efficiency is improved.