The invention discloses a method of cyclic comprehensive utilization of a glyphosate mother solution and utilization of boiler flue gas energy, and belongs to the technical field of chemical engineering. The method of cyclic comprehensive utilization of the glyphosate mother solution and utilization of boiler flue gas energy comprises the procedures of oxidation, deamination, crystallization, concentration, atomizing, drying, combustion, hydrolyzing and the like. The method can achieve sufficient recycling of various kinds of resources in the glyphosate mother solution, and meanwhile utilizesthe boiler flue gas as a heat wind source of the atomizing and drying procedures, and thus the waste heat of the boiler flue gas can be sufficiently utilized. The method of cyclic comprehensive utilization of the glyphosate mother solution and utilization of boiler flue gas energy can sufficiently utilize the waste heat of the boiler flue gas, reduce the recycling cost of the glyphosate mother solution, and improves the production benefits.