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发明公开
CN108299245A 一种N，N′-双（3-二甲基氨基丙基）脲的合成工艺 有权

一种N，N′-双（3-二甲基氨基丙基）脲的合成工艺
摘要：
本发明公开了一种N，N′-双(3-二甲基氨基丙基)脲的合成工艺，首先将N,N-二甲基-1,3-丙二胺溶于有机溶剂中，与二(三氯甲基)碳酸酯反应得到N,N′-双(3-二甲基氨基丙基)脲的盐酸盐；然后加碱液中和得到N,N’-双(3-二甲基氨基丙基)脲水溶液，随后经共沸分水、过滤除盐、蒸馏除去溶剂后得到目标产物N，N′-双(3-二甲基氨基丙基)脲。本发明合成工艺的产品收率高、纯度高、简便易操作、三废少、适合工业化采用。
摘要（英）：

The invention discloses a synthetic process for N,N'-bi(3-dimethylaminopropyl)urea. The synthetic process comprises the following steps: firstly dissolving N,N'-dimethyl-1,3-diaminopropane in an organic solvent, reacting with bi(trichloromethyl)carbonate to obtain hydrochloride of the N,N'-bi(3-dimethylaminopropyl)urea; and adding alkaline liquor for neutralizing, so as to obtain an N,N'-bi(3-dimethylaminopropyl)urea water solution, and removing the solvent through azeotropic water separation, filtration desalination and distillation, so as to obtain a target product of the N,N'-bi(3-dimethylaminopropyl)urea. The synthetic process is high in product yield, high in purity, simple and convenient in operation, and less in three wastes, and suitable for industrial application.

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