Sole (22), particularly for shoes, that has a plantar-like perimetric shape and is constituted by a plurality of layers which comprise at least one supporting structure (23), for plantar support, which is elastic and on an upper surface (24) of which there is at least one seat (27, 27a, 27b) for at least one mid-sole (10, 10a, 10b). The mid-sole (10, 10a, 10b) is constituted by a body (11) from the lower surface (14) of which a first plurality and a second plurality of elastically compressible protrusions (15, 16) protrude downward, each one having an axial cavity (17a, 17b).