The invention discloses a treatment method for chlorination alkali quenching in production of sucralose-6-acetate. The treatment method comprises the following steps: after chlorination reaction is finished, carrying out reduced pressure distillation to obtain an organic solvent used in a chlorination process, and obtaining a material subjected to organic solvent removal; adding alcohol substancesinto the material for dissolving and then carrying out alkaline quenching treatment. According to the treatment method for the chlorine and alkali quenching in the production of the sucralose-6-acetate, disclosed by the invention, the organic solvent is obtained by direct reduced pressure distillation, heat required by distilling the organic solvent after cooling and neutralizing is reduced, andthe problems caused by direct addition of alkali for quenching after chlorination in the prior art are solved; no colloidal materials are produced and no by-product sucralose is generated in the reaction process; meanwhile, the use amount of the alkali is greatly reduced; in addition, the system pH value is close to neutral after quenching is finished, and no acid is added for adjusting the pH value, thereby simplifying the production process and greatly reducing the production cost.