The invention discloses a method for manufacturing a multi-layer laminated barrier membrane with a good barrier property. The method is characterized in that the barrier membrane is of a five-layer structure, that is, a membrane base layer, a plastic base layer, a membrane base layer, a purification membrane and an insulating layer in sequence from bottom to top, the layers are laminated one by one by using a lamination machine, and the lamination temperature is controlled within 20-60 DEG C. The scratching resistance of the barrier membrane is improved, the service life of the barrier membrane is prolonged, meanwhile the barrier effect of the barrier membrane is improved, and the barrier membrane is good in practicability and convenient to popularize and use.