A shaking prevention, clamping and orienting device for a sliding door comprises a base body which is provided with two parallel track grooves; the shaking prevention, clamping and orienting device for the sliding door further comprises buffer springs, spherical balls and rotary orienting pins; the inner surface of an outer wallboard of each track groove is provided with at least two pivot joint holes in the height direction of the base body, and the pivot joint holes intersect with the track grooves; a track partition plate of the two track grooves is provided with at least two buffer holes with one ends being open, and the center lines of the buffer holes are perpendicular to the length direction of the base body, and the open ends of the buffer holes interact with the track grooves; therotary orienting pins are arranged in the pivot joint holes; the buffer springs are arranged in the buffer holes, one ends of the buffer springs are matched with the closed ends of the buffer holes,and the other ends of the buffer springs are matched with the spherical balls; the spherical balls are kept in the open ends of the buffer holes and extend into the track grooves. When a door body moves in the track grooves, the rotary orienting pins are rotated, and the spherical balls are rotated at the same time; and when the door body is not perpendicular to the horizontal plane, the sphericalballs compress the buffer springs to adjust the posture of the door body, the noise is lowered, and the service life is prolonged.