The invention relates to a method to assist with driving a vehicle, implemented by a mobile device and comprising steps of: connecting (21) with a peripheral for measuring at least one physiological parameter of a driver; receiving (22) measurements of the physiological parameter; and determining (23) a state of health of said driver from the physiological parameters received, characterised in that it also includes steps of: connecting (24) with a computer of a vehicle; selecting (25) a profile associated with said driver, said profile including associations between predetermined states of health, as well as configuration parameters of the vehicle; determining (26) configuration parameters of the vehicle from the predetermined state of health and the selected profile; and transmitting (27)the predetermined configuration parameters to the computer of the vehicle.