The invention discloses an ecological slope protection system with framework slope protection combined with sand drain water seepage and water diversion slopes. The ecological slope protection systemcomprises a slope top water channel which is evenly provided with a plurality of drainage outlets, and each drainage outlet communicates with a roadbed water channel at the bottom of a slope through aslope drainage channel; and the bottom of the slope top water channel is evenly provided with a plurality of vertical sand drains connected to greening units, and the slope surface is further provided with framework units. According to the ecological slope protection system disclosed by the invention, by combining the framework units and the greening units, landslide mass is protected from sliding; meanwhile, the friendly development of engineering and environment is ensured, and large-range infiltration of rainfall does not occur through the slope top water channel and the slope drainage channel, and necessary water resources are provided for growth of plants, so that the rhizomes of the plants form a natural protection net in the slope, not only the stability of side slopes is protected, but also contribution to restoration of ecological environment is made; and the ecological slope protection system has high practical value.