The invention provides a workflow operation method based on a grid operation management system. A graphical application based on a workflow module is constructed, and the application is mainly used for building a high-level grid application function which meets the requirements of future development and has the intelligent, graphical, standard and integrated characteristics. The application can solve various types of problems met by a dispatching unit at each level in an informationization field, such as the self-defining of flow, the building of a unique workflow, the unification of the format and standard of the workflow. The method meets the requirements of continuous development of the current dispatching informationization.