The invention belongs to the field of a teaching device, relates to a desk and particularly relates to a multifunctional desk and chair combination for preventing students from shortsightedness. The multifunctional desk and chair combination comprises a desk and a chair matched with the desk; the desk comprises a desk board and desk holes beneath the desk board; both sides of the desk holes are provided with desk legs, and the desk legs are arranged beneath the desk board; a fixing pole is arranged between the desk legs, and the middle part of the fixing rod is provided with a locking hole; the bottom part of the chair is provided with an adjusting rod, and the adjusting rod crosses through the locking hole; the chair comprises a base fixedly connected with the adjusting rod and a flexibleair cap on the base; a seat board is arranged on the flexible air cap, and one end of the seat board far from the desk is provided with a backrest; the backrest is perpendicular to the seat board, and a reading panel is arranged on the desk board and can be overturned. The multifunctional desk and chair combination is simple in structure, convenient to process, and suitable for large-scale popularization and use.