The invention discloses a mining/setting-up integrated mining technology without tunneling and coal pillars, which includes the following steps: selecting a mining area and dividing the mining area into large section working surfaces and small section working surfaces; performing construction of in-advance guiding roadways and setting in-advance open-off cuts, thus completing preparation work of mining; firstly, mining the small section working surfaces, after two of the small section working surfaces are mined, mining the large section working surfaces in a retreating mining mode, wherein theutilized secondary small section retrained roadway is subjected to roof cutting and pressure relieving for secondary roadway retraining, and a Y-shaped ventilating system is formed in the large section working surfaces; then performing secondary cyclic mining, wherein the utilized small section retrained roadway in the secondary circulation is subjected to secondary roof cutting and roadway retraining so that a Y-shaped ventilating system is formed in the large section working surfaces; and alternately mining the small section working surfaces and the large section working surfaces until themining area is mined completely. The method is free of crossheading tunneling and is free of coal pillars, allows continuous mining, and has important significance of increasing resource recovery ratein a mine, reducing tunneling, increasing production efficiency, cutting payrolls and increasing efficiency, and has great practicability.