The invention discloses a protection device of a centrifuge for a laboratory. The protection device comprises a protective cover outer shell, and a protective cover inner shell is arranged in the protective cover outer shell; the horizontal distance of the protective cover outer shell and the protective cover inner shell is 2 cm; a protective cover taking opening is formed in the top of the protective cover outer shell; protective covers with the same shape and size are arranged in the position, opposite to the protective cover taking opening, at the top of the protective cover inner shell; the protective covers are perpendicularly connected with the protective cover outer shell; and a clamping ring bulge is arranged at the lower part of the side surface of the protective cover outer shell. According to the protection device, noise and vibration generated during operation of the centrifuge are effectively reduced, the body of a user is protected, leakproofness of the bottom of the protection device is guaranteed, the problem that a liquid inside leaks and pollutes the environment is solved, the user can observe the working condition inside, some emergency situation can be timely treated, and irreversible damage is avoided.