The invention relates to a novel nano-silicon fertilizer, and a preparation method and a use thereof. The novel nano-silicon fertilizer is characterized in that the novel nano-silicon fertilizer comprises, by mass, 1-30% of nano-silica, 50-89% of palm oil, and 10-20% of epoxy resin, and the novel nano-silicon fertilizer is prepared through compounding the epoxy resin with the palm oil as an oil carrier, and mixing with the nano-silica. The surface of a common fertilizer granule can be wrapped with the novel nano-silicon fertilizer, so the nano-silicon fertilizer is uniformly distributed on thesurface of the granular fertilizer, closely adheres to the granular fertilizer, does not fall off, does not cause dusts, and avoids wastes. The novel nano-silicon fertilizer also can prevent the granular fertilizer from caking, and is helpful for reducing the anti-caking agent use cost of manufacturers of composite fertilizers and other fertilizers. The granular fertilizer is uniformly wrapped with the nano-silicon fertilizer, so the nano-silicon fertilizer can be uniformly sprinkled together with the granular fertilizer in a mechanical sowing manner during subsequent use in order to reduce manpower.