The invention discloses a device for monitoring human body surface resistance by applying an internet of things sensor. The device comprises a biological voltage generation module, a biological electric current high resistance detection module, a biological data processing module and an information sharing module; a signal output end of the biological voltage generation module is connected with asignal input end of the biological electric current high resistance detection module, a signal output end of the biological electric current high resistance detection module is connected with a signalinput end of the biological data processing module, and a signal output end of the biological data processing module is connected with a signal input end of the information sharing module; the biological voltage generation module is formed by a biological micro voltage generation circuit; the biological electric current high resistance detection module is formed by a biological electric current high resistance conversion circuit, the biological data processing module is formed by a microprocessor and an biological information array, and the information sharing module is formed by an internetof things access module.