The invention discloses a preparation technology and application of a modified non-water dispersible polyacrylate pressure-sensitive adhesive. The preparation technology comprises the following steps:by taking a thin-film material as a base material, carrying out separant and corona treatment, coating a treated base material with an adhesive taking ethyl acrylate, butyl acrylate and methyl methacrylate as main ingredients, and carrying out a series of processing steps such as drying and curing, compound isolation, batching, cutting and packaging, thus obtaining the pressure-sensitive adhesivefinished product, and the prepared modified non-water dispersible polyacrylate pressure-sensitive adhesive has the characteristics that low temperature resistance and high temperature resistance arebetter, condensable volatile matters are fewer, mass loss rate is low and no harmful gas escapes. Meanwhile, the invention also discloses application of the modified non-water dispersible polyacrylatepressure-sensitive adhesive obtained by the preparation technology in light industry manufacturing industries such as sanitary napkins, diapers, double-faced adhesive tapes and clothing.