The invention belongs to the field of bubble wine, and relates to rose-flavor health-keeping wine. The rose-flavor health-keeping wine is prepared by the following raw materials by weight: 1500-2000 parts of white wine, 20-30 parts of rice, 15-25 parts of mannose oligomer powder, 10-20 parts of fried wheat, 2-7 parts of shrimp powder, 21-25 parts of highland barley powder, 10-20 parts of litchi rind, 10-25 parts of truffle, 10-15 parts of lycium, 5-8 parts of radix stemonae, 1-3 parts of folium mori, 4-7 parts of millet, 7-10 parts of gastrodia elata, 4-7 parts of rose, and 7-10 parts of loofah sponge. The health-keeping wine has the efficacy of benefiting Qi and nourishing blood, tonifying spleen and nourishing stomach, tonifying Qi and stopping diarrhea, strengthening tendon and increasing physical strength, dehumidifying and sweating, tonifying life, strengthening physique and delaying senescence through drinking for a long time, and has the characteristics of simple preparation method and low cost, and is suitable for large-scale industrial production.