The invention discloses an intelligent replacement device of vehicle brake oil. The device comprises a shell, an oil extracting mechanism, an oil injecting mechanism and an oil-water separator; the oil extracting mechanism and the oil injecting mechanism are mounted in the shell; the oil extracting mechanism comprises an oil extracting flow transparent viewing window, an old oil barrel and a vacuum generator with a silencer; one end of the oil extracting flow transparent viewing window is connected with four ways of oil extracting pipes, and the other end of the oil extracting flow transparentviewing window is connected with the old oil barrel; the old oil barrel is connected with a vacuum generator with a silencer; the vacuum generator is connected with the oil-water separator; the oil-water separator is connected with an external air source; an oil extracting valve is arranged between the old oil barrel and the oil-water separator, and is serially connected with the vacuum generator; the oil injecting mechanism comprises an oil injecting flow transparent viewing window and a new oil barrel; one end of the oil injecting flow transparent viewing window is connected with an oil injecting pipe, and the other end of the oil injecting flow transparent viewing window is connected with the new oil barrel with the brake oil; the new oil barrel is connected with the oil-water separator; and an oil injecting valve is arranged between the new oil barrel and the oil-water separator. The device can improve the replacement efficiency of the vehicle brake oil, reduces introduction of air, improves the brake system safety, is visual and more thorough in oil replacement, and saves the labor cost.